Our whole brain was in a hot stressed state, Then nearly fourteen minutes ago expansion started. Wait... The skin began to cool, The eyes began to fool, The pain developed cruel, We closed the door (we switched off the light), Photophobia, phonophobia, nausea, raveling mysteries, That all started with the big bang! I have a recent paper in the The Journal of Mathematical Neuroscience that looks into the nucleation and subsequent growth processes of cortical ion imbalances (MAD and T. Isele: Transient localized wave... Read more
Markus Dahlem: ABOUT THE AUTHOR
Markus A. Dahlem studied physics in Germany. He worked in mathematical biology, biomedical engineering, computational neuroscience, and neurology in the US, Brazil, Great Britain, and Germany.
Having broad expertise in both mathematics and neurology, he is interested in neuromodulatory techniques that begin to revolutionize the treatment of patients with refractory primary headaches.
Together with Klaus Podoll he founded the Migraine Aura Foundation, a non-profit organization, with the goal to provide material that helps patients to recognize and understand their neurological symptoms during migraine.
Currently, he is at the Humboldt-Universität zu Berlin in the Cardiovascular Physics Lab leading an independedd research group "Dynamics and Neuromodulation of Migraine" supported by the Bernstein Network within a German-USA Collaboration in Computational Neuroscience.
Markus Dahlem: All Posts
New paper on the arXiv. Theoretical neuroscience complements experimental and clinical neuroscience. We provide a theoretical analysis of a second-generation Hodgkin-Huxley (HH) formalism, that has been used before in models for muscle cells (myocytes) and pancreatic beta-cells, but not in models of brain cells (neurons) to better understand pathological stress conditions in migraine and stroke. The HH formulation of action potentials is certainly one of the most successful models in mathematical biology. It describes an essential part of cell-to-cell communication... Read more
Would you dare script the mother say, “I lied, I don’t really have breast cancer”? Two days ago, a petition on Change.org appeared that I would like you to consider signing. Change.org is the go-to site for Web uprisings and although I support several petitions there, I usually do not blog about it. This case is different as many might not even see the problem, which makes it a rather perfidious problem deserving more attention. First, let me cite from... Read more
Are their any signs of heightened consciousness in dying brains? Or is it just a wave of death as others have called it—more sober: a latency to unconsciousness. A new study  suggests exactly that, namely heightened consciousness in rats after cardiac arrest. First of all, whatever the brain's briefly lasting (~30s) high frequency oscillations mean, they are not new. The paper—though an elegant study with some new results from what I can see on the first glimpse—seems to completely... Read more
"A text was not something fixed and eternal but the product of the reader’s mind in conjunction with the author’s". That's just one sentence in the ongoing debate on Virginia Heffernan's text "Why I'm a creationist" from a week ago. I follow Virginia (@page88) and every now and then read her articles ever since she wrote a good piece about health information online—should we worry about hypochondriacs or rather hypocrisy? February 2011, Virginia, then still writing for the NYT Magazine,... Read more
On my way back to Germany with my flight being delayed, I have some time to write about the International Headache Congress that I've visited here in Boston. We had many good talks, some about still unpublished data, so I'd rather not write about these research topics here—and my flight is anyway not that much delayed. But one thing is quite remarkable, the hashtags #IHC2013 and #migraine were trending on Twitter for three days. On the last IHC2011 in Berlin,... Read more
It's called spherical cow by myself and others. In The Big Bang Theory it became spherical chickens in a vacuum: A simple model that is either used for back-of-the-envelope calculations or one that is actually useless. Let's forget such jokes and go beyond simple models that are rather calculations, let's go somewhere really much more interesting. I will tell you the story of so-called toy models, in particular their place in science within what might be seen as three categories... Read more
A long time ago, I heard that my great uncle—he was only referred to as Uncle Sepp—collected butterflies. Someone in my family mentioned it. Actually, Uncle Sepp was a butcher. He lived in New Jersey. (I can't but think of Satriale's Pork Store.) Last month, when I was there, in Newark at the NJIT, it got me interested again. Uncle Sepp is already about 30 years dead, but still. Over Christmas, I asked again in my family. His name was... Read more
I am on my way to the FENS-IBRO-Hertie Winter School "Brain Dynamics and Dynamics of Brain Disease". My slides are here. I am quite happy to see that it actually becomes less remarkable that brain dynamics in disorders like Parkinson's disease, epilepsy, autism, schizophrenia, sleep disorders, stroke, and---not least--- migraine should be described in terms of mathematics. Of course, there is no other language for dynamics. Now, we even have a Winter School devoted to the topic. Already Freud thought... Read more
Some time ago, we published a paper in PLoS ONE on early migraine symptoms called migraine aura. These symptoms can be mapped onto the human cortical surface. We used individual drawings of the visual field defects in visual migraine aura and MRI scanner readings from the same person. (The annotation is in German. "rechtes Gesichtsfeld" means "right visual hemifield" and "linke Sehrinde" menas "left visual cortex") A neurologist at the University of Utah, KC Brennan, reports now that once we... Read more