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Part 2 of 2: Inflammation and Exercise: friend or foe?

Posted 25 August 2011 by Kausik Datta

As I mentioned in Part 1 of this two-part post, inflammation is a two-edged sword, requiring a fine balance between initiation and termination, in order to promote health and not disease. With this idea in mind, I came across a recent review article by Gleeson et al. in Nature Reviews Immunology, which focuses on the anti-inflammatory effects of exercise and its implications in health and disease.1 The authors observed that pathogenesis of various conditions associated with many metabolic and other... Read more

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Part 1 of 2: Inflammation: A two edged sword

Posted 25 August 2011 by Kausik Datta

Inflammatory mechanisms are very important for the innate defence system of the body. When the host body encounters stimuli it perceives as harmful, such as pathogens and/or products thereof, injured cells or tissue, or any foreign object that irritates the surrounding tissue, the host often responds with a complex generalized response. A part of this response involves vascular tissues, leading to increased translocation of circulating white blood cells (WBC or leukocytes), especially the granule-containing cells (such as neutrophils) and mononuclear... Read more

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