heart disease

 

The Largest Cell Therapy Trial in Heart Attack Patients Uses Hardly Any Stem Cells

Posted 28 February 2014 by Jalees Rehman

One of the world’s largest clinical cell therapy trials has begun to enroll 3,000 heart attack patients, some of whom will have bone marrow cells extracted with a needle from their hip and fed into their heart using a catheter in their coronary arteries. The BAMI trial has €5.9m in funding from the European Commission and will be conducted in ten European countries. Enlisted patients will be randomly assigned into two groups: one group will receive the standard care given... Read more

Bone Marrow Cell Infusions Do NOT Improve Cardiac Function After Heart Attack

Posted 18 April 2013 by Jalees Rehman

For over a decade, cardiologists have been conducting trials in patients using cells extracted from the bone marrow and infusing them into the blood vessels of the heart in patients who have suffered a heart attack. This type of a procedure is not without risks. It involves multiple invasive procedures in patients who are already quite ill, because they are experiencing a major heart attack: 1) Patients with a major heart attack (also referred to as ST-elevation Myocardial Infarction or... Read more

Can The Heart Regenerate Itself After A Heart Attack?

Posted 5 December 2012 by Jalees Rehman

Some cardiovascular researchers believe that the heart contains cardiac stem cells or progenitor cells which can become mature cardiomyocytes (beating heart cells) following an injury and regenerate the damaged heart. The paper "Mammalian heart renewal by pre-existing cardiomyocytes" published in the journal Nature by Senyo and colleagues (online publication on December 5, 2012), on the other hand, suggests that the endogenous regenerative potential of the adult heart is very limited. The researchers studied the regeneration of cardiomyocytes in mice using... Read more

Recent Study Raises Questions About Using Adult Stem Cells for Chronic Heart Disease

Posted 15 November 2012 by Jalees Rehman

A recent clinical study (POSEIDON Randomized Trial) investigated the effects of transplanting bone marrow derived adult stem cells into patients with known heart disease. The results were presented at the 2012 American Heart Association (AHA) meeting in Los Angeles and also published in the article "Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy: The POSEIDON Randomized Trial". The article by Dr. Joshua Hare and colleagues appeared in the online... Read more