The Rise and Fall of the Boston Patients

8 December 2013 by Nathalia Holt, posted in Uncategorized

A little over a year ago I first wrote about the Boston patients. These two men took us on an unusual journey this year. It began in 2010 when Timothy Henrich, then a fellow at Brigham and Women’s Hospital, was looking for a new research project. What he stumbled onto was a novel way of pursuing a cure for HIV. This week we learned that two men who were once considered as nearing a cure are actually not. Although it seems like this news should be a disappointing blow to the HIV research field, it actually gives us new insight into how to fight the virus.


Timothy Henrich was inspired by the story of Timothy Ray Brown. Timothy, suffering from acute myeloid leukemia, received a novel therapy that treated both his cancer and his HIV infection. He received two bone marrow transplants from a donor who was naturally resistant to HIV. This donor was resistant to HIV thanks to a mutation called CCR5Δ32. The CCR5 gene is almost always necessary for HIV to enter human cells. People missing 32 tiny bits of the gene have natural resistance to HIV because the virus can’t enter their cells.


Timothy received mutant cells that went on to make a brand new immune system in his body. This new immune system was one that HIV couldn’t invade. Stopping antiviral therapy in 2007, he has never gone back on the medication. This is called a functional cure. Timothy may have some virus hidden in his body but he remains off therapy; cured.


Henrich, starting a new research project, was interested in how Timothy’s cure worked. He wanted to understand how HIV hides in the body. Even if a person has been on antiviral therapy for decades with no detectable virus in their blood, once they stop taking drugs, the virus will return. Henrich wondered what role the bone marrow transplant Timothy received played in his cure. To test this he analyzed samples from two men who, like Brown, had cancer and HIV. Unlike Timothy, the bone marrow transplants they received were not CCR5Δ32 and therefore not resistant to HIV. Henrich wasn’t trying to cure anyone. So imagine his surprise when he found the samples he analyzed contained no hidden HIV. The results were announced at the AIDS 2012 conference to an excited crowd. After careful consideration, the team decided to take the two men, now named the Boston patients, off antiviral drugs. Could they, Henrich wondered, control the virus on their own just like Timothy?


The early results were promising. The virus seemed to be held at bay.  The news was unprecedented and undeniably exciting. So it was a blow to learn this week that just 4-8 months after stopping therapy the virus came back. The Boston patients weren’t protected by the bone marrow transplants.


The news is disappointing-especially for these two men who may have briefly dreamed of a life without antiviral drugs. But for HIV research, the news is not a crushing blow; instead the returning virus gives us a new clue about how to cure the infection.


The news isn’t discouraging because bone marrow transplants were never the answer to curing HIV. Bone marrow transplants are dangerous procedures. Approximately 30% of people receiving a transplant from a donor do not survive. No researcher would give a person living with HIV a bone marrow transplant unless it was needed to treat their cancer. The Boston patients were never the answer to curing HIV. Instead, they’re the signposts on the path. Henrich wanted to know what role a bone marrow transplant played in Timothy Brown’s cure. We now can postulate that it wasn’t the transplant alone. This in itself is valuable. It rouses us to further support therapies based on genetic resistance to HIV. The rebounding virus inside these two men tells us the extent of how HIV hides in the body. It reveals the importance of pursuing gene therapy for HIV. Multiple clinical trials are looking at how to use gene therapy to create an immune system that makes the cells in the body look like CCR5Δ32-the mutation keeping the virus controlled in Timothy. They deserve our support more now than ever.


Although we never like hearing about a therapy that doesn’t work or when a virus returns, these cases tell us that when pursuing a cure, we are on the right path.

9 Responses to “The Rise and Fall of the Boston Patients”

  1. MADAM VICKY Reply | Permalink

    I have been suffering hardship from HIV/AIDS since 7yrs now, and i happen to have 2 kids for my husband, and now we cannot proceed to have another kids all because of my disease and now i have do all what a human like i and my husband can do just to get my disease healed, i have went to several places to seek for help not even one person could ever help, until i melt a comment on the daily news paper that was commented by Desmond about how this powerful traditional doctor help him get cured of the disease (HIV-AIDS) " my fellow beloved" i firstly taught having a help from a spiritual traditional healer was a wrong idea, but i think of these, will i continue to stress on these disease all day when i have someone to help me save my life?" so i gather all my faiths and put in all interest to contact him through his Email address at , so after i have mailed him of helping get my disease cured, he respond to me fast as possible that i should not be afraid, that he is a truthful and powerful doctor which i firstly claimed him to be. So after all set has been done, he promise me that i will be healed but on a condition that i provide him some items and obeyed all his oracle said. I did all by accepting his oracles fact and only to see that after some weeks of taking his herbal medicine i notice some changes in my body system and i went for check up the day he ask me to go for check up to confirm if the sickness was still there,to my greatest surprise i could not find any sickness in my body i was first shocked and later arise to be the happiest woman on earth after i have concluded my final test on the hospital by my doctor that i am now HIV- Negative. My papers for check are with me and now i am happy and glad for his miraculous help and power.
    With these i must tell everyone who might seek for any help, either for HIV cure or much more to contact him now at these following email now,
    " sir thank you so much for your immediate cure of my disease, i must say a big thanks for curing my disease, i owe you in return. Thanks and be blessed sir.

  2. Deborah Reply | Permalink

    i was having sexual problem and genital herpes, no body want to near me or have sex with me because of my genital herpes... one night i browse through the internet and read alot of testimonie about a great spell caster that have healed all disease. i contacted him about my genital herpes and semen leakage, and the spell catser told me to stop eating meat since i,m going to use his ADURON SPIRITUAL HEALING HERBAL REMEDY DRUGS. a week later after taking ADURON SPIRITUAL HEALING DRUGS i was cure totally and my semen leakage stop instantly, i,m so happy for my life now, thanks to dr shant tami the spell caster. call this spell caster to cure your sickness is genuine spell caster +2348115435381 or is email address

  3. Michaelsmith Reply | Permalink

    This is real take it serious, who will believe that a herb can cure five years HIV in my body, i never believe that this will work i have spend a lot when getting drugs from the hospital to keep me healthy, what i was waiting for is death because i was broke, one day i hard about this great man who is well know of HIV and cancer cure, i decided to email him, unknowingly to me that this will be the end of the HIV aids in my body, he prepare the herb for me, and give me instruction on how to take it, at the end of the two week, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me negative, i thought it was a joke, i went to other hospital was also negative, then i took my friend who was also HIV positive to the Dr, after the treatment she was also confirm negative . He also have the herb to cure cancer please i want every one with this virus to be free, that is why am dropping his email address, do email him he is a great man. you can as well call his number on +2348135200383,or visit the link to know more about him government is also interested in this DR, thank you for saving my life, and I promise I will always testify for your good work.

  4. Stella Lucas Reply | Permalink

    Been a HIV positive is just like been through hell but EVERYTHING IS POSSIBLE. So amazing and i want to testify of the good work done by DR. TELEMI a very strong and powerful spell caster. DR. TELEMI has proved science and scientists wrong for believing and thinking that there is no cure for HIV AIDS but to be sincere this GREAT MAN is so real and powerful. I never thought that this spell will work but this GREAT MAN has proved it to me and it has worked and still working perfectly. My Name is Stella Lucas and i was diagnosed of the deadly disease called HIV AIDS in 2010 and i thought that was the end and there will be no hope. Speaking to anyone was always a problem because i was so worried and always in the state of unrest in fact i thought it was over until one blessed day when i was searching for help here on the internet, i came across a testimony about DR. TELEMI on how he has helped so many people on many issues in life, a lady who was HIV positive got cured by him, how he cured cancer, and he made so many women to be pregnant, and how he has cast a powerful spell to restore broken marriages and so on. At first i thought it was all a lie but i decided to give it a try since there was no option and, when i contacted this MAN he laughed and told me that, that is too small for him to handle but i was still in doubt, and he gave me a form to fill which I did, and he instructed me on what to do and i OBEYED him completely as he told me. Then he sent a parcel to me and it was a holy water and a pure holy oil as described by DR. TELEMI. I took the holy water and the holy oil and after taking it, he told me to go for check up but I was still in doubt and was so afraid to go for the test but i took a bold step and believed that it is well, and i believed all what he has done and all that he has told me. So i went to the hospital for the test it was so amazing, awesome and exciting what seems to be impossible became possible, the VIRUS disappeared completely from my system and I was tested HIV negative. Quickly I called him and told him what happened he congratulated me and today i am a happy woman again the way things use to be. Don't you think that this testimony is worth sharing? I promise to tell the world about him and i will keep sharing this testimony till the end because many people has died of AIDS and i want many people who believed that it is over to know that EVERYTHING IS POSSIBLE AND I WANT THEM TO GET HELP FROM THIS SPELL CASTER by contacting him on his email at for your solution now. If you are hiv positive and you think that it is over i want to tell you that there is hope for you and if you truly and dearly value your life please contact him now. THIS IS REAL HE IS NOT A SCAM, BELIEVE HIM AND DON'T ASK TOO MUCH QUESTIONS. Thank you DR. TELEMI and May your good gods keep rewarding you for your good deeds.

  5. Rea Rivera Reply | Permalink

    Dr.okoh with a heart of gratitude, i want say thanks to you for curing me from HIV disease and to let know to world about my happiness.i want to say God will bless you and your household for your good works. I'm Rea Rivera, from Manila Philippine, i was confirm HIV positive and i was just living with the help of medication.i came across a comments on a blog how Dr.okoh cured her, i was really shocked but i contacted him and now I'm cured also. I will continue to talk about your good works just the same way people have been talking about how you cure them from their HIV disease, I'm happy now. you can contact him If you have any problem or you are also infected with any disease, kindly contact him now with his Email: or call him on +2348110745051

  6. Clara Morgan Reply | Permalink


    My name is Clara Morgan from united states, i am here to thank DR peter the powerful spell caster that rescue me from HIV AIDS. I was diagnosed of this disease in the year 2012, and because of this, i was very unhappy with my life, and i went into research on how i can get cured, i contacted alot of spell casters and none of them could help me rather than scammed me and took away my money without helping me. All this period of my life, i was sad and unhappy so one day as i was in the internet a decided to sign in a friend guestbook, only for me to see was a testimony of a lady on how she was helped by DR peter, so i was confused to contact him at the moment because i didn't want to be scammed again but after one week, i decided to contact him, so when i contacted him, he assure me that he will help me and i told him that many spell casters has also told me this but they all scammed me, he told me not to worry that he is going to help me, So i believe in him because all i wanted was to be cured, so he prepared a healing spell for me and told me to wait for just 24 hours, after 24 hours, i went to the hospital for test and to me happiness the test stated that i was cured from the disease.. This gladdens my heart and everybody in the hospital was surprised even the Medical Doctor, So viewers DR peter is a God Gifted man and can help you to cure all types of sickness like HIV AIDS, CANCER, PILE, KIDNEY PROBLEM, SYPHILIS, DIABETES and lot's more. You can contact him through his email on ( . For more details you can reach me on my ID: or you can call +2347055620537

  7. johin bobby Reply | Permalink

    Hello I'm johin bobby by name, I'm giving a testimony about Drunuigbe the great Herbalist, he has the cure to all manner of diseases, he cured my herpes disease, though I went through different website I saw different testimonies about different spell casters and herbalist, I was like: 'Many people have the herpes cure why are people still suffering from it?' I though of it, then I contact Drunuigbe via email, I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared it (CURE) and sent it to Airfreight Online Courier Service for delivery, he gave my details to the Courier Office, they told me that 3-5 days I will receive the package and i took the medicine as prescribed by him and I went for check-up 2 weeks after finishing the medicine, I was tested herpes negative, if you are herpes positive do me a favor for you to contact him and I will try my possible best to make sure you get cured, when you contact him, make sure you tell him that I referenced you.. contact him +2349051176418, contact me on

  8. lisa abigail Reply | Permalink

    My name is lisa Abigail, from United states,
    i have been a HIV positive is just like been
    through hell; well special thanks to God
    almighty for using Dr. Enoma, the greatest
    spell caster in curing my HIV disease. I was
    diagnosed of this disease in the year 2004.
    Thou I was taking my medications but I was
    not myself. Until last two weeks. My friend
    came to me and told me that he saw many
    testimonies on how a spell caster cured people
    HIV disease. Thou I never believe in spell, I
    said to myself "seen is believing" I took his
    name and searched it on GOOGLE, I saw
    many testimonies myself. Quickly, I copied his I emailed
    him, he gave me a form to fill which I did,
    then he called me and told me that his gods
    required some items in which he will use in
    casting a curing spell on me and he told me
    that it will cost me some money of wichI sent to him
    because I could not find the items. He bought
    the items and prepared a cure for me, then he
    have sent a parcel to me through courier
    delivery service. I paid the courier services, I
    got my parcel, it was a holy water as
    described by Dr. Enoma I took the holy water
    and after taking it. He told me to go for check
    up, I went to the hospital and to a HIV test, I
    was tested HIV negative. Quickly I called him
    and tell him what happened he congratulated
    me. I promise to tell the world about him. You
    can contact via or call + 2348146244808

  9. veronica adams Reply | Permalink

    Hello readers,I am mrs adams veronica,I am from london united kingdom,I was an HIV-AIDS patient and I got it from cheating on my husband,It was sort of a payback,but a week later I was told by a friend that the person who I cheated with had HIV-AIDS and did not tell me,I was so stupid by not protecting myself,I thought since he was an old school friend he was trustworthy,But I was wrong,I cried and cried,Two days later, I got a phone call from my friend and she told me about a person who is known by another friend, who can
    Help me,I could not let my husband know what I was Passing through,I finally got his email address [] and I send a message to this man about my story through his email and he replied me immediately saying i should be calm and told me that everything will be fine,I could not
    come to terms with what I was hearing,but then I concluded that it does not matter because I was so broken up,I just needed help,I was going out of my mind literally,I was confused with what he was telling me,but I listened,He told me about some materials I need to buy that he needed to cast the spell and I said OK and I bought the materials,i sent down my picture to him and my positive result sheet and
    he replied me that i am going to be negative under 3 days,I message Him every 2hours for 2day and I knew he thought that I was crazy but I did not care,I needed a shoulder,Behold,the third day he messaged
    me and he told that i should go for a test,that i will be negative,My marriage could be broken because of a stupid mistake and my life was on the line,I remembered when I was going to get the results of my re-test I called him up again and told him that I was going to get my results today and his reply was “so" and that everything will be as he explained,I knew then that he was getting tired of me calling him, maybe I was wrong,Well I got my results and the first person I called up was him - again,As he said hello I started to cry and cry,i could not believe it,I was given a second chance in life,This man is a great spiritual HIV/AIDS healer,his healing spell on aids healing is
    very powerfull,please brothers and sister,contact. Dr. Latifat on his email address:,he can heal any kind of sicknesses and diseases,you can contact him,his requirement is not hard.

Leave a Reply

two + 3 =